Medicine who invented it
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His colleagues had to pick up his work load which, unsurprisingly, caused resentment. Whilst the ENT endoscopy device was being developed - it launched in - Dr Chaturvedi applied to study biodesign at Stanford University in the US as part of a fellowship funded by the Indian government.
On his return, he set up a company focused on bringing more medical devices to market, including a tool to help chronic sinusitis, and a nasal foreign body extractor. As though that wasn't enough, he also has a sideline as a stand-up comedian, performing a handful of shows a month. Last year he launched a platform to connect Indian doctors with those working in the innovation industry. In the UK another junior doctor also discovered a gap in the system - and the market.
Dr Lydia Yarlott was frustrated at the time colleagues wasted every shift trying to contact each other to discuss patients or medical information. They were using inefficient, old-style pagers, radios and telephone landlines. Many medical staff resorted instead to using WhatsApp and other messaging apps. But Dr Yarlott says that such platforms are "tools for social media not for clinical healthcare".
It was a scary feeling. When she mentioned the daily struggles staff were facing to Philip Mundy, an entrepreneur, one evening after work, they then joined forces to work on a solution. With fellow doctor Barney Gilbert, they set up Forward Health, a secure messaging app. Nurses who trained there went on to work all over the United Kingdom. They took with them everything that they had learned about sanitation and hygiene, proper hospital planning, and the best ways to achieve health. Childbed fever was fatal in 25 to 30 percent of sporadic cases and 70 to 80 percent of epidemic cases.
She promoted the education of women in medicine. He demonstrated its effectiveness to the public using 50 sheep.
All 25 of the unvaccinated sheep died, but only one vaccinated sheep perished, probably from an unrelated cause. He later received the first Nobel Prize in Physiology or Medicine. It was a synthetic version of salicin, which they derived from the plant species Filipendula ulmaria meadowsweet. Within 2 years, it became a global commercial success. His lab also discovered arsphenamine Salvarsan , the first effective treatment for syphilis. These discoveries were the start of chemotherapy.
This discovery changed the course of history, saving millions of lives. He later pioneered artificial organs. Gilman and Louis S. Goodman discovered the first effective cancer chemotherapy drug, nitrogen mustard, after noticing that soldiers had abnormally low levels of white blood cells following exposure to nitrogen mustard. With Harold Harrison, he created the first electrolyte-glucose solution for clinical use.
John Heysham Gibbon, an American surgeon, invented the heart-lung machine. He also performed the first ever open-heart surgery, repairing an atrial septal defect, also known as a hole in the heart. He also developed the first inkjet ECG printer.
Black, a Scottish doctor and pharmacologist, invented the first beta-blocker after investigating how adrenaline affects the functioning of the human heart. The drug, Propranolol, is a treatment for heart disease. Black also developed cimetidine, a treatment for stomach ulcers.
Sternbach, a Polish chemist, discovered diazepam Valium. Throughout his career, Sternbach also discovered chlordiazepoxide Librium , trimethaphan Arfonad , clonazepam Klonopin , flurazepam Dalmane , flunitrazepam Rohypnol , and nitrazepam Mogadon. John Enders and colleagues developed the first measles vaccine. It became available in Walton Lillehei, an American surgeon, carried out the first successful human pancreas transplant.
Lillehei also pioneered open-heart surgery, as well as new equipment, prostheses, and techniques for cardiothoracic surgery. Maurice Hilleman, an American microbiologist and vaccinologist, produced the first mumps vaccine. Hilleman developed over 40 vaccines , more than anybody else. Cyclosporine also treats psoriasis and other auto-immune conditions, including severe cases of rheumatoid arthritis.
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